The Tale of Trump and the Woke Trans Mice

Hey everyone, with Trump 2. 0 underway, along  with the most orchestrated attack on science America has ever seen, you’re probably  going to be hearing a lot from me about the orange clown and his breathtaking science  illiteracy. Today’s installment is about some alleged blue-haired ultra-woke transgender  mice and the millions of dollars that Biden wasted on them.

Let’s get into it. So this all started when Trump addressed Congress on March 4th, vomiting up a long list  of alleged extravant expenses that the previous administration put upon the poor unwitting  taxpayers, gloriously uncovered by president Musk and his DOGEball team. The whole speech is  a circus side show from top to bottom, and we could dig into virtually every single one of his  ludicrous claims, but let’s focus on this one.

8 million dollars for making  mice transgender. This is real. No, it isn’t real.

If you made a list of  not real things, this would be pretty high up on there. Transness is not something that  applies to mice, nobody is making trans mice, he’s just saying “trans” because transgender  issues is one of the topics in the pathetic culture war he’s waging that riles up his idiot  supporters. Naturally, thousands of intelligent people called out this utter bullshit, mocking  him relentlessly for saying such an idiotic thing, and we will explain in more detail than  you want to hear how idiotic it is in just a moment.

But first, this is how the president of  the United States decided to respond to thousands of scientists fact-checking his ridiculous claim. Wrong, you guys! Biden totally did it!

Those fake news losers at CNN tried to fact check me but I  was right, as usual, because I’m always right, because I’m such a smart special boy,  like my mommy always told me! You guys, this is not a tweet. This is not a  blog post.

This is from whitehouse. gov. The official website for the white house. 

This is what America has become. The man who holds the highest office in the  country, and arguably the world, talks like a bratty teenager in official white  house communications. We’re halfway to idiocracy, and I’m not being even remotely hyperbolic.

President of America! I got a three point plan to fix everything. Break it down Camacho! 

Department of government efficiency. DOGE. Getting chills?

Well tough shit, because it’s a  FACT, you guys! Biden spent 8 million dollars to turn mice trans! You know, those dirty  “transgender experiments” that are totally a real thing.

Then he lists the grant amounts and  titles of the studies, the end. Well that’s very convincing, Mr President, but first of all,  8 million dollars is a completely negligible fraction of the 6 trillion dollar federal  budget, especially compared with the tens of billions of dollars sent to Israel over  the past year and half for the sole purpose of murdering Palestinian children, a convenient  omission from your little list. But beyond that, some people actually know what all of these words  mean, even if your cronies don’t.

I mean, maybe the 19-year old DOGE staffer who goes by the name  “Big Balls” knows what some of these words mean, he seems like a real wunderkind, but I wouldn’t  bet any of his rich dad’s popcorn money on it. Anyway, they were kind enough to attach a  document linking to all these proposed studies, so let’s go through every single one of these  10 scary grants with “trans” in them and explain what they’re actually about. Spoiler alert, there  isn’t any waste, fraud, or abuse in any of them, so let’s teach Trump a little science.

First up: Molecular Mechanisms of Hormone-Mediated Sex Differences in Wound Healing. If someone took five seconds to read the first sentence of this grant, they  would see that the first thing they address is that the cost Americans as a population spend  on treating chronic wounds, or those that don’t heal within 6-12 weeks, something which affects  1 in 50 people, is roughly $100 billion per year. Doing the math, 340 million over 50, 100 billion  dollars over all those people, that’s 15 grand apiece.

Assuming there is no healthcare mechanism  to assist all these individuals, something which Donald “Obamacare is the devil” Trump truly wants  to be a reality, that means one out of every 50 of us might have to spend almost 15 thousand dollars  out of pocket. Sounds like this research could reduce the cost and improve the efficiency of  treatments that millions of people will need, for a collective tax investment of a measly $450  thousand. They also mention other afflictions that this research could have relevance towards. 

Weird, nothing about transgenders yet. Then they summarize what we know so far,  that there seems to be a correlation between someone’s sex at birth and their ability to  heal wounds. Apparently men, on average, are worse at healing wounds than women.

Interesting.  They go on to say that researchers have noticed testosterone and estradiol might specifically  have some important role in these processes, but things get really confusing because it also  looks like they might not be doing the same thing when examining men vs. women.

It would be better  experimental control if we could study the effect of men taking testosterone or estradiol vs. not  taking them, and also the effect of women taking testosterone or estradiol vs. not, so that we can  figure out exactly what is going on here.

They mention that examining transgender individuals  would be a good idea, because sometimes this is part of treatment for trans individuals. They are  talking about controls. They want to utilize the fact that trans people exist in order to control  for sex to understand what a hormone does in an XX individual vs.

what it does in an XY individual.  They don’t even know if the effect of estradiol is different between sexes. They want to do that  experiment, and of course we always test such things on mice first.

They talk about testosterone  affecting the immune system and how they want to learn more about that interaction in XX vs XY  animals. Nothing so far about asking the mice their preferred pronouns. They are just looking at  how exogenous, meaning externally applied hormones might improve or hinder wound healing that  they think is acting through the immune system, and how it works depending on whether you have  XX or XY sex chromosomes.

That’s it. They used the word “transgender” once in a sentence  just to say “hey, it might be a good idea to take a closer look at trans people getting  healthcare, because it might give us useful data to help understand wound healing and save  people money”, but that’s too triggering to Sir Groper Cleveland, so we won’t get that benefit. By the way, whichever braindead intern threw together this cute little document for Trump  decided to highlight the most triggering quotes in the grants.

Apparently, they were the most  upset about “We developed new models and showed that T [testosterone] limits wound healing in  large animals with different effects in XX vs. XY animals. ” Controls are super woke and lame, guys. 

Chronic wounds are much better. Kill the study. Also, we should remember that grants in science  are very competitive, with an application success rate of roughly 20-25%, and reviewed by a  panel of competing scientists within the relevant field who would absolutely love to  take a giant shit on your research proposal if they see a discrepancy in your logic.

If these  grants sounded like an absolute waste of money, they would get trashed. Moving on. A Mouse Model to Test the Effects of Gender-affirming Hormone Therapy on  HIV Vaccine-induced Immune Responses.

Trigger warning: This grant contains scary words  acknowledging that trans people exist. If you have the testicular or ovarian fortitude to get  past the scary bits about trans people receiving healthcare, since they are in fact people, then  we can move on to the science. Like the previous grant, they mention how sex hormones such as  testosterone appear to influence the immune system, but those pesky sex chromosomes keep  adding noise to the data.

They say they could sort out the noise from the data if we could just  control for sex differences. They specifically are interested in how vaccine treatments  induce differential immune responses between the two sexes, and looking at gene expression  differences within a sex could be an interesting way to generate hypotheses about what might be  going on. Wait a minute.

Weren’t there people in real life complaining about vaccine efficacy  needing more research? I seem to recall a bunch of people whining about a recent vaccine being  “experimental” and how we were all “guinea pigs” and they “killed millions of people”. For those  people to be consistent with their wrongness, you’d think they’d be interested in experiments  that could inform us about how we can prevent negative responses to vaccines, yeah? 

Especially if it looks like there might be sex-specific differences? Oh, but we would  have to be able to control for sex. So their experimental model is essentially apply some  amount of hormone to mice of a specific sex, administer the vaccine, and look at the genes that  respond.

It sounds like if there are treatments outside of gender-affirming care that involve  hormonal treatment, and there are, it could inform us about vaccine safety that affects those  completely non-trans people as well. Crazy, huh? The most triggering parts of the grant according  to, let’s call the intern Rory, were apparently, “We propose to develop an animal model  of feminizing hormone therapy to study the effects of estrogen/anti-testosterone therapy  on HIV vaccine-induced immune responses” and “we will develop a mouse model of XHT (Cross-sex  hormone therapy) that recapitulates clinical hormone therapy for male-to-female transition  in humans.

” See this word, model? In science, developing a model means to create a  representation of a system for the purpose of making predictions. We don’t make “weather models”  by creating literal isolated weather systems.

We don’t actually recreate the early universe at  the Large Hadron Collider. Likewise, in biology, we don’t literally create transgender mice. They  are models used to mimic real-life phenomena, and can be used to ask a variety of questions  depending on the limits of the model.

Again, there are multiple good scientific reasons  for studying hormonal effects within a sex, and transgender healthcare is just one extension  of direct application from this model. Apparently, it’s just too much to handle that trans people  are one of the immediate beneficiaries of this research, so let’s just ignore research that  could help anyone who receives any vaccine. Very on theme for His MAGA-sty.

Number three: Reproductive Consequences of Steroid Hormone Administration. They start off talking about how there are few studies on the effects  of cross-sex hormones on fertility. This might be a good point to remind everyone that  there are numerous health issues that stem from an imbalance of endogenous hormones.

So a study like this could easily pertain to what we know about a multitude of hormonal  disorders including polycystic ovary disorder, which is thought to be due to an increase  in male hormone production in women, affecting around 10% of the female population. They comment on the lack of data on transgender individuals. Again, let’s remind ourselves that  there is a scientific reason to want to control for sex when studying hormones due to innate  differences on average, and trans individuals just so happen to fit the bill as perfect patients for  observing these effects in humans.

By extension, controlling for sex in mice provides a powerful  experimental model to test hormonal treatments, with the authors stating, “This model provides a  powerful tool to clarify the effects of T therapy on reproductive phenotype and function, in a  manner not possible in humans. ” Despite all the things we could learn about fertility in  men and women, the fact that the repercussions could include providing healthcare to  trans people is much too scary. So, we are now banning controlling for sex.

Sorry  to the 1 in 10 men and women who struggle with infertility, Donald says go fuck yourself. According to Rory, the key triggering statements in this grant were “the impact of long-term  cross-sex hormone therapy on reproductive health is largely unknown, particularly in transgender  men (female-to-male or FTM)” and “None of the existing animal models that address the effect of  androgens on reproductive function in females are directly applicable to the clinical paradigm  of cross-sex T therapy in transgender men or GnRHa-T therapy in transgender adolescents. To  address this knowledge gap, we have developed a mouse model to mimic T treatment for FTM  gender transition.

” So, to summarize: “There is a knowledge gap” and “current models cover x  relevant health issues, and they designed one that covers x+1 relevant health issues. ” Apparently  increased efficiency gives Donnie D Cups the runs, so let’s cut him some slack. Moving on: Cross Sex Steroid Therapy and Cardiovascular Risk in the Transgender Female.

Again, we need to get past the scary words talking about trans individuals  and get into the actual science. They mention that their observations that individuals that  were born male and receive hormones for gender affirming treatment have an increased risk for  cardiovascular disease. So presumably, there is a molecular mechanism underlying this phenomenon. 

The words talk about the benefits to trans people, but by understanding the science associated with  it, this research can easily apply to cisgendered people. If we understand the effects of hormone  x in males vs. females on cardiovascular health, we can come up with better treatments for anyone  with cardiovascular issues.

They end with how this grant will improve their skills, which is  a sign that it was written by a student. So, they defunded a graduate student and their  science that would contribute to knowledge about cardiovascular disease because it contains  words about transgender people. But who cares about people with cardiovascular  problems?

If you eat nothing but McDonald’s every day, you deserve to die, right? Rory found this grant particularly triggering, as he/him highlighted several sections of it.  “The Alexander laboratory has developed a novel model of feminizing hormone therapy in the male  rat that involves administration of E2 to mimic physiological levels observed in age-matched  female rats in conjunction with androgen suppression.

” In other words, they control for  sex when applying hormones. “A critical need involves the use of innovative animal models to  provide reliable risk assessment and in-depth investigation into mechanisms that contribute  to increased CV risk in adult [transgender females] individuals that undergo GAHT. ”  Yes, this would benefit trans women directly, because that is the most direct application from  the model.

Oh no! Then they won’t die as much! It will also add to our knowledge on mechanisms  underlying cardiovascular diseases in general, and in a way that can only be done by controlling  for sex before applying hormones.

Controls bad! Trump smash! “Aim 1 will test the hypothesis  that the shift in the hormonal milieu in gender affirming hormone therapy in a rodent model  of the transfemale rat is associated with increased end organ damage and cardiovascular  risk that is further exacerbated with preexisting chronic disease.

Aim 2 will test the hypothesis  that increased end organ damage and cardiovascular risk in transgender females that undergo gender  affirming hormone therapy involves an estradiol induced ‘male sex-specific’ effect on the renin  angiotensin system. ” Translation: Aim 1 tests whether a hormone treatment cocktail used in a  real-life treatment will influence cardiovascular disease. They simply use an intervention that  contains relevance in real life.

Scientists try to squeeze as much out of their data as possible.  Why wouldn’t they use a similar hormone treatment that could be applicable to humans? That’s not  fraud, that’s called efficiency.

It’s starting to seem like they just did a search for the word  “transgender”, read literally nothing else, and pulled the money just to add an item to  Trumpelstiltskin’s dumb speech, huh? Next up: Gender-Affirming Testosterone Therapy on  Breast Cancer Risk and Treatment Outcomes. This one starts with the obvious direct benefit  to trans individuals.

Their experimental design of controlling for sex is also ideal for looking  at effects of miRNA and testosterone on mammary gland development, carcinogenesis, and breast  cancer treatments, as they point out in the very next sentence. This sentence could confuse a lot  of people, so imagine how the Trump team took it. Micro-RNAs are small non-coding RNA molecules  that regulate gene expression.

Carcinogenesis is when normal cells become cancer cells. The  rest you probably know. Anyway, by examining the effects of testosterone levels in females,  we can learn about how breast cancer is affected by differences in testosterone levels, which  could be beneficial to the 1 in 8 women who are at risk of developing breast cancer.

You’d think  Trump would give tits a pass, but not this time. They make a note that the mouse studies here are  particularly useful compared with human studies because the rate of aging in mice is much faster,  while breast cancer development appears to be very similar in mice, meaning they can learn about  breast cancer at a much faster rate by using mice studies. And if testosterone has an interaction  with the development of breast cancer, wouldn’t it make sense to learn about this interaction so  we can potentially make new drugs and learn about negative interactions with existing treatments and  the various types of breast cancer?

Why would we not do this? Oh, because it could also help trans  people? Maybe it makes sense if you ingest bleach, eh Donny?

If they had been able to get through one  paragraph, they would have seen, “These knowledge will have direct implications for understanding  BC risk and open up new avenues of treatment for cisgender men and women as well. ” Oh well. It’s  funny how Diaper Don talks a big game when it comes to “helping kids” with cancer, and is happy  to use kids with cancer in a political stunt, but then actively defunds research that  can help cancer patients, huh?

What’s next? Microbiome mediated effects of gender  affirming hormone therapy in mice. They specify that we don’t know how certain  hormone treatments that are provided before puberty affect skeletal development.

This  includes those used for non-gender affirming care: prostate cancer, endometriosis,  and central precocious puberty. They want to know how blocking or inducing certain  hormones can affect skeletal development. The microbiome has also been shown to be a factor in  skeletal development, so they design experiments that include fecal transplants to disentangle  effects from either mechanism.

Would you want to know about side effects of a treatment  on your child if they needed hormone therapy before puberty? Would you like to help ensure the  health of children with cancer or reduce pain in young women with endometriosis? Mango Mussolini  says no, let’s not, since it will also benefit trans people.

What’s next? Androgen effects on the reproductive neuroendocrine axis. This one should be clear as fucking day, but let’s break it down anyway.

Androgens are hormones  typically associated with the development of male characteristics in humans, including testosterone.  Although present in much lower quantities, females still produce testosterone and other androgens  endogenously. Some females produce more or less on average.

Levels fluctuate throughout the  menstrual cycle and typically decrease with age. First word down, lets continue: Androgen effects  on the reproductive neuroendocrine axis. The neuroendocrine axis refers to the hypothalamus,  anterior pituitary, and an end-organ system through which hormones are released based on a  multitude of inputs received from throughout the body, creating hormonal feedback loops that can  regulate physiological functions including body weight, thermoregulation, hunger, fatigue,  and reproduction, to name a few examples.

The grant title refers to the “reproductive”  aspect of the endocrine system. Putting it together, the title of the paper suggests they  want to look at the effect of male-associated sex hormones on the reproductive aspects of the  endrocrine system. Once again, females also produce androgens which act through the endocrine  system and ensure normal reproductive function.

They propose looking at the effect of androgens  on a specific type of cell called hypothalamic kisspeptin neurons which produce surges of  luteinizing hormone involved in a complex cascade of events that ultimately affects  reproductive capabilities in men and women. The experiments they propose are to monitor  reproductive aspects of trans men receiving healthcare, because they often are treated with  exogenous androgens as part of their healthcare, which we can then compare to women who  are not treated with androgens. The other experiment involves using a transgenic  mouse model, presumably by genetic ablation of kisspeptin neurons via kiss1 knockout,  though it’s not specific in the abstract, to determine to what extent the effects of  androgens act through the kisspeptin neurons.

The results from the experiments laid out in the  grant could be informative to menstrual health, reproductive health, and cancers acting through  this system, in addition to trans health. It’s important to note that just because a  grant is funded through an initiative that aims to address knowledge gaps in the literature,  this doesn’t mean that its benefits are entirely limited to the scope of the initiative.  As we went over in the previous grants: Yes, of course they benefit trans people.

But  they also benefit cis people because the models they’ve described thus far provide a framework  to make predictions in multiple forefronts of science. That means the experiments were  well-designed. Read for yourself.

“Indeed, high levels of exogenous androgens fundamentally  contribute to reproductive disruption seen in otherwise healthy women and transgender men  (female sex individuals taking high levels of androgens)”. Oh look, that’s pretty neat, they  say right in the grant that it’s applicable to both cis and trans individuals. I guess the E for  efficiency in DOGE really just means control+f search “trans” and delete without knowing what the  fuck you are actually deleting.

Great work, Elon. Let’s look at what triggered Rory on this  one. “This proposal includes clinical studies of transgender individuals and the effects of  androgen treatment on their reproductive health.

” Yup, that’s the fucking experimental design,  genius. It’s like getting triggered by someone explaining the ramps and pulleys in high school  physics class that will test Newton’s laws. “We test this hypothesis in two complementary Aims  that study the role of high exogenous androgens in both a clinical setting in transgender male  (female sex) human subjects and corresponding transgenic female mouse models.

” Using  complementary experiments to corroborate results just makes it good science. It’s so painfully  obvious that they just grab the statement they think makes the Tangerine Dram appear vindicated,  when in fact they just look like complete morons that don’t understand what’s being described  in the slightest. But wait, there’s more!

GHB Toxicokinetics: Role of sex hormone  dependent monocarboxylate transporter regulation and potential for altered  overdose risk in transgender men and women. The researchers state that preliminary data  show that toxicokinetics regarding GHB, Gamma-hydroxybutyrate, commonly referred to as the  “date-rape” drug, are altered in the presence of female sex hormones. This is supported by previous  research showing that hormonal changes associated with the estrous cycle, or mammalian fertility  cycles generally, may act through monocarboxylate transporters in the kidney, which are the  same transporters important for GHB clearance.

The research questions they want to test  are: 1. Do individual sex hormones affect GHB clearance? 2.

Does testosterone make GHB  overdose more likely? The only way to address these questions properly is to control for sex  before applying treatment. Not controlling for sex will decrease effiency of the science  by adding unnecessary noise to the data, making analysis more complicated and wasting  money, assuming this research is possible at all without these controls.

If you can’t understand  that and are still fuming about trans mice, you’re a dumb bigot, probably of an orange tint. The quotes that Rory pulled from this one really show how obsessed these idiots are with  their caricature of transgender culture. “Gamma-hydroxybutyrate (GHB), is a popular drug  of abuse utilized at raves.

” Yes, people abuse drugs at raves, and also in offices,  homes, streets, many places. Shall we study the drugs then? No?

“Use of GHB has  been increasing in the LBGTQ community due to the prevalence of a phenomenon referred  to as chemsex. ” Wow, some people do drugs, some people have sex, and some people even do  both at the same time. Let’s all clutch our pearls about the horrors of the real world.

If  Presipumpkin could stop fixating on “chemsex” he might understand that this could also inform  us on how to treat date-rape victims generally. If we know that certain individuals  can have worse reactions to the drug, and we know why, we can design treatments to  combat the overdose. Still more, you guys.

Gonadal hormones as mediators of  sex and gender influences in asthma. This is probably the dumbest inclusion on this  list. It is literally just proposing that we look at sex differences on asthma phenotypes.

They  have data showing that the inflammatory response in asthma might be triggered by estrogen. Women  who go through fertility treatments often take estrogen. This is not a crazy wacky idea.

They  want to do experiments to look at the effects of estrogen on inflammatory mechanisms in mice  with XX and XY chromosomes. They’re not making transgender mice. They are looking at the  inflammatory response in male mice and in female mice with or without exogenous estrogen. 

It’s mind-boggling how simply having the word “gonad” in the grant frightens these toolboxes to  the point that it depletes all rational thinking. They don’t have the brain power to get past the  scary words. Rory even specifically pulled out the statement, “We expect that our studies would serve  to develop potential sex- and gender-specific treatments and recommendations for dosage of  therapeutic agents to treat and prevent asthma in cis and transgender women.

” It literally  says cis AND trans women. So I guess they just don’t give a shit about women in  general. Who cares about their asthma, right?

We need the money to pay for Elon’s super  cool exploding rockets that load the atmosphere up with metal oxides and nitrogen oxides. Plus all  the child support. Finally we get to the last one.

Understanding how chromosomal  makeup and cross-sex hormone administration affect wound healing in mice. Reports had been floating around that transgender patients had worse healing outcomes than other  populations. Additionally, this pattern doesn’t seem to be equal between sexes.

From this  observation, they propose that testosterone might inhibit mechanisms of wound healing. This  grant wants to observe trans patients undergoing hormone therapy and complement it with a mouse  model. Basically, the same fucking thing we’ve been saying this whole time.

The researchers  are just doing the best experiment to figure out what hormones do to the body without giving  a shit whether it involves trans people or not, it’s just an element of experimental control. But  the best part is the last sentence in the grant, which they conveniently did not acknowledge  and probably didn’t even read. “By filling this knowledge gap, this research may ultimately  offer improved wound healing and personalized medicine therapies to not only transgender  patients but all patients.

” But who cares about “all patients”, right? That doesn’t sound  like an important demographic to the Donald, or any of the bloodsuckers in his inner circle. So that’s it for the ten woke trans-loving grants that Trump cancelled to save a few bucks.

There  are a few obvious takeaways here. First, none of them wanted to “make trans mice”. Second, all of  them referred to trans individuals as a way of controlling aspects of hormone administration  within a specific biological sex in order to see their affects on a particular aspect of  animal physiology.

And third, all of them outlined studies whose results would benefit  all humans, not just trans people. Of course we should also note, that no matter how angry  it makes conservatives, trans people do exist, making up around 1% of the population or more,  and they matter just as much as cis people, so even if the studies were actually only  applicable to trans people, which they aren’t, it still would merit spending a few million  dollars, which again, is completely negligible in the grand scheme of government spending. Trans  people deserve to benefit from research that they pay into through taxes, just like cis people. 

Given the total NIH budget of $48 billion, I think we can allow this 0. 0002% of NIH  grant funds to benefit 1. 6% of the population.

On a scientific level, the arguments used to deny  funding for these grants that have already been approved by scientists as good use of tax dollars,  are tired and pathetic. We’ve heard these types of caricatures before. Sarah Palin, vice presidential  nominee for John McCain in 2008, made comments about fruit fly research being a waste and taking  money away from disability research.

This idiot doesn’t know that there is a Drsophila-based  center for research into autism at the University of North Carolina which has provided decades worth  of high quality and ground-breaking research, including the discovery of genes being transmitted  via chromosomes. The role of hox genes in embryonic development. And molecular mechanisms  of circadian rhythms.

Many scientists have written extensively on why this type of ignorance is  dangerous. Other examples of silly sounding science weaponized by clueless politicians  include the “shrimp on a treadmill” fiasco, which was used as justification to decrease  funding to science, even though it had important implications on the effects of water quality  on wildlife survivability. Researcher Lawrence Tabak was under fire from critics claiming that  tax money was wasted sending toenail clippings through the mail.

His response encapsulated  the ignorance of such critiques in a quote, stating, "What's scientifically sound and indeed  cost-effective — to collect biospecimens for cancer research — was twisted in what was intended  to ridicule an important life-saving research effort," which is basically the same playbook  being used right now to defund science by claiming that scientists are “making transgender mice. ” The lesson that I desperately wish Trump and his peanut gallery would learn is that you can’t make  knee jerk judgements about scientific research without understanding the science. Some of the  most groundbreaking science sounds silly when reduced to one-liners.

Studying worm vulvae led  to understanding retinoblastoma. Looking at how green algae phototax in response to light led  to the discovery of a suite of genes that are involved in the rare developmental disorder  Bardet-Biedl syndrome. Looking at how algae swim led to insights into lung diseases including  primary ciliary dyskinesia.

In science, we call these “phenologs,” or phenotypes that may have  no relevance between organisms but derive from evolutionarily conserved molecular mechanisms.  These can lead to funny-sounding studies, but it is a valid and successful approach  to studying disease mechanisms. Weaponizing provocative one-liners like “transgender  mice” to stir up drama doesn’t just affect science related to transgender individuals, it  affects most of the research that we all want and directly benefit from.

Oh, and it makes you  sound like a fucking idiot, Donald. Just a tip. Thus ends the story of Trump and the woke  trans mice.

A cautionary tale that in a normal timeline would be getting the Trump  laughed out of office, but instead we have to endure this sheer insanity on a near daily  basis, for an unspecified duration of time. What will the next debacle be? We’ll just  have to wait and see.

Until next time.